I think antibiotics are a good and useful technology. Since Alexander Fleming’s discovery of penicillin in 1927 it has saved many thousands, perhaps millions, of lives. Antibiotics, in and of themselves, are not bad. The problem we have with them is misuse. Fleming warned, early on, that if penicillin was used at too low a dose or for too short of a time it would lead to antibiotic resistant bacteria. We ignored his advice.
In 1947, a hospital in London experienced an outbreak of staph infections that did not respond to penicillin. By 1953, the same resistant bug sparked an epidemic in Australia. In 1955 it crossed to the United States, infecting more than ore 5,000 mothers who had given birth in hospitals near Seattle –and their newborns too.
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In 1948 Thomas Jukes, a poultry nutritionist at Lederle Laboratories, fed a few ounces of the left over growth medium from the production of the newly discovered broad-spectrum antibiotic tetracycline or aureomycin to a group of chicks. The results in increased growth rates were amazing as were the short-term health benefits.
Jukes shared his results with some colleagues and the practice of feeding low levels of antibiotics to livestock spread like wildfire. This enabled the start of the CAFO industry and was the beginning of the lethal game of leapfrog that organisms and antibiotics have engaged in ever since.
This item was originally posted to a previous issue of Doc' Holliday's Blog on 21 March 2018
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